HitPredict

Interactor 1: YTH1 (Q06102)
mRNA 3'-end-processing protein YTH1 (Yeast 30 kDa homolog 1)
Gene: YTH1

Interactor 2: CFT2 (Q12102)
Cleavage factor two protein 2 (105 kDa protein associated with polyadenylation factor I)
Gene: CFT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.714

Property	Details
Experiments	11805826, 16429126, 30737185, 16554755, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex GO:0006397 - mRNA processing GO:0030846 - termination of RNA polymerase II transcription, poly(A)-coupled
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 208 Sc			1 859
+	Hs
		317868 CPSF4_HUMAN (1-178): 1.31e-58: 187: 39.46		CPSF2_HUMAN (14-859): 0: 765: 19.40
+	Sp
		251804 YTH1_SCHPO (4-174): 7.13e-42: 141: 38.37		CFT2_SCHPO (5-859): 0: 668: 22.53
+	At
		69168 CPSF_ARATH (12-117): 2.04e-14: 73: 23.36		CPSF2_ARATH (16-859): 0: 729: 21.02
+	Hs
		317873 CPSF4_HUMAN (1-178): 1.31e-58: 187: 39.46		CPSF3_HUMAN (10-468): 6.1e-151: 461: 16.99
+	Sc
		985883 YTH1_YEAST (1-208): 5.83e-71: 216: 100.00		YSH1_YEAST (2-430): 2.45e-134: 421: 15.86
+	Hs
		64099 CPS4L_HUMAN (1-167): 7.26e-50: 161: 35.06		CPSF3_HUMAN (10-468): 6.1e-151: 461: 16.99
+	Sp
		142963 YTH1_SCHPO (4-174): 7.13e-42: 141: 38.37		YSH1_SCHPO (10-444): 8.67e-135: 421: 15.89
+	At
		69150 CPSF_ARATH (12-117): 2.04e-14: 73: 23.36		CPS3B_ARATH (6-488): 1.2e-133: 413: 15.32