HitPredict

Interactor 1: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Interactor 2: LAIR1 (Q6GTX8)
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) (hLAIR1) (CD antigen CD305)
Gene: LAIR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	10903717, 9285412
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 593 Hs			1 287
+	Hs
		665902 PTN6_HUMAN (6-593): 0: 531: 55.27		LAIR1_HUMAN (1-287): 5.63e-103: 303: 100.00
+	Mm
		665995 PTN6_MOUSE (6-583): 0: 530: 55.94		LAIR1_MOUSE (16-287): 2.9e-74: 229: 40.22
+	Hs
		665921 PTN6_HUMAN (6-593): 0: 531: 55.27		LIRB4_HUMAN (1-246): 1.52e-56: 190: 25.59
+	Hs
		798184 PTN11_HUMAN (1-593): 0: 581: 100.00		KI2L3_HUMAN (1-162): 4.77e-38: 138: 21.82
+	Hs
		798232 PTN11_HUMAN (1-593): 0: 581: 100.00		KI3L1_HUMAN (1-154): 1.94e-35: 133: 21.66
+	Hs
		986023 PTN11_HUMAN (1-593): 0: 581: 100.00		KI2L4_HUMAN (1-162): 3.9e-35: 131: 24.85
+	Hs
		798139 PTN11_HUMAN (1-593): 0: 581: 100.00		KI2L1_HUMAN (1-162): 1.22e-32: 124: 20.61
+	Mm
		719307 PTN11_MOUSE (1-593): 0: 580: 99.49		LRB4A_MOUSE (21-286): 1.86e-31: 121: 18.22
+	Hs
		665820 PTN6_HUMAN (6-593): 0: 531: 55.27		KI2L3_HUMAN (1-162): 4.77e-38: 138: 21.82
+	Hs
		665821 PTN6_HUMAN (6-593): 0: 531: 55.27		KI3L1_HUMAN (1-154): 1.94e-35: 133: 21.66
+	Mm
		719293 PTN11_MOUSE (1-593): 0: 580: 99.49		LIRB3_MOUSE (23-150): 7.81e-17: 82.6: 19.23
+	Mm
		719316 PTN11_MOUSE (1-593): 0: 580: 99.49		Q8K4V6_MOUSE (21-155): 4.72e-16: 79.9: 20.71
+	Hs
		665819 PTN6_HUMAN (6-593): 0: 531: 55.27		KI2L1_HUMAN (1-162): 1.22e-32: 124: 20.61
+	Mm
		665991 PTN6_MOUSE (6-583): 0: 530: 55.94		LRB4A_MOUSE (21-286): 1.86e-31: 121: 18.22
+	Hs
		665916 PTN6_HUMAN (6-593): 0: 531: 55.27		LIRB2_HUMAN (28-150): 6.91e-23: 99: 24.00
+	Hs
		665922 PTN6_HUMAN (6-593): 0: 531: 55.27		LIRB1_HUMAN (28-150): 2.12e-22: 98.7: 23.20
+	Hs
		252776 PTN6_HUMAN (6-593): 0: 531: 55.27		LIRB3_HUMAN (28-156): 1.39e-20: 93.4: 22.90
+	Mm
		665982 PTN6_MOUSE (6-583): 0: 530: 55.94		LIRB3_MOUSE (23-150): 7.81e-17: 82.6: 19.23
+	Hs
		616999 PTPRD_HUMAN (39-522): 2.1e-115: 379: 26.76		LIRB4_HUMAN (1-246): 1.52e-56: 190: 25.59
+	Hs
		616953 PTPRD_HUMAN (39-522): 2.1e-115: 379: 26.76		KI2L1_HUMAN (1-162): 1.22e-32: 124: 20.61