HitPredict

Interactor 1: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Interactor 2: CDC73 (Q6P1J9)
Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)
Gene: CDC73

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	35938192, 21726809, 26742426
Identification Methods	enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation, phosphatase assay
Interaction Type	direct interaction, physical association, dephosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 593 Hs			1 531
+	Hs
		665903 PTN6_HUMAN (6-593): 0: 531: 55.27		CDC73_HUMAN (1-531): 0: 824: 100.00