HitPredict

Interactor 1: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Interactor 2: SIGL9 (Q9Y336)
Sialic acid-binding Ig-like lectin 9 (Siglec-9) (CDw329) (Protein FOAP-9) (CD antigen CD329)
Gene: SIGLEC9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	15703304
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 593 Hs			1 463
+	Hs
		986060 PTN11_HUMAN (1-593): 0: 581: 100.00		SIGL7_HUMAN (20-463): 5.28e-84: 268: 75.33
+	Hs
		665971 PTN6_HUMAN (6-593): 0: 531: 55.27		SIGL9_HUMAN (10-463): 1.38e-95: 297: 100.00
+	Hs
		665970 PTN6_HUMAN (6-593): 0: 531: 55.27		SIGL7_HUMAN (20-463): 5.28e-84: 268: 75.33
+	Hs
		545101 PTN11_HUMAN (1-593): 0: 581: 100.00		PVR_HUMAN (14-407): 2.63e-56: 193: 18.77
+	Mm
		682308 PTN11_MOUSE (1-593): 0: 580: 99.49		CEAM1_MOUSE (60-368): 2.72e-28: 119: 15.56
+	Hs
		177596 PTN11_HUMAN (1-593): 0: 581: 100.00		SIGL5_HUMAN (34-463): 1.35e-25: 111: 17.76
+	Hs
		986018 PTN11_HUMAN (1-593): 0: 581: 100.00		SIG11_HUMAN (73-462): 9.19e-25: 109: 21.04
+	Hs
		589567 PTN11_HUMAN (1-593): 0: 581: 100.00		CD33_HUMAN (140-461): 2.13e-24: 105: 19.22
+	Hs
		986013 PTN11_HUMAN (1-593): 0: 581: 100.00		SIG10_HUMAN (42-460): 5.38e-22: 101: 15.56
+	Hs
		581691 PTN11_HUMAN (1-593): 0: 581: 100.00		VCAM1_HUMAN (103-341): 2.93e-17: 86.4: 20.16
+	Mm
		719313 PTN11_MOUSE (1-593): 0: 580: 99.49		SIG10_MOUSE (166-459): 6.41e-11: 66.7: 10.22
+	Hs
		177594 PTN6_HUMAN (6-593): 0: 531: 55.27		SIGL5_HUMAN (34-463): 1.35e-25: 111: 17.76
+	Hs
		665942 PTN6_HUMAN (6-593): 0: 531: 55.27		SIG11_HUMAN (73-462): 9.19e-25: 109: 21.04
+	Mm
		665976 PTN6_MOUSE (6-583): 0: 530: 55.94		CD22_MOUSE (8-351): 1.81e-24: 108: 16.29
+	Hs
		589559 PTN6_HUMAN (6-593): 0: 531: 55.27		CD33_HUMAN (140-461): 2.13e-24: 105: 19.22
+	Hs
		665940 PTN6_HUMAN (6-593): 0: 531: 55.27		SIG10_HUMAN (42-460): 5.38e-22: 101: 15.56
+	Hs
		590601 PTN6_HUMAN (6-593): 0: 531: 55.27		CD22_HUMAN (20-351): 3.41e-20: 95.8: 14.37
+	Hs
		68228 PTPRS_HUMAN (39-522): 8.52e-117: 384: 26.76		HECA2_HUMAN (7-368): 1.05e-15: 81: 18.73
+	Dm
		1308480 Q9W4F5_DROME (191-560): 1.41e-112: 371: 29.38		Q9BN17_DROME (27-335): 2.76e-18: 90.2: 21.04
+	Hs
		68222 PTPRF_HUMAN (33-522): 2.6e-112: 371: 25.85		HECA2_HUMAN (7-368): 1.05e-15: 81: 18.73