HitPredict

Interactor 1: KDSR (Q06136)
3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) (Short chain dehydrogenase/reductase family 35C member 1)
Gene: KDSR

Interactor 2: HSDL1 (Q3SXM5)
Inactive hydroxysteroid dehydrogenase-like protein 1 (Short chain dehydrogenase/reductase family 12C member 3)
Gene: HSDL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	adh_short~adh_short
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 332 Hs			1 330
+	Hs
		1312485 DHRS4_HUMAN (11-276): 8.59e-84: 256: 21.19		DHRS4_HUMAN (22-321): 3.2e-81: 249: 20.13
+	Dm
		1248591 Q8SX57_DROME (29-280): 1.47e-80: 247: 22.48		Q8SX57_DROME (62-322): 7.35e-76: 235: 22.14
+	Hs
		1121042 DHRS7_HUMAN (18-329): 4.21e-79: 246: 21.73		DHB12_HUMAN (25-329): 1.42e-74: 234: 40.72
+	At
		1338081 TRNHF_ARATH (26-285): 1.11e-81: 250: 23.19		TRNHC_ARATH (60-321): 1.51e-73: 229: 21.97
+	At
		1338080 TRNHF_ARATH (26-285): 1.11e-81: 250: 23.19		SAG13_ARATH (56-321): 3.71e-73: 228: 20.15
+	Dm
		1248593 Q8SX57_DROME (29-280): 1.47e-80: 247: 22.48		Q9VNF3_DROME (62-322): 1.56e-73: 229: 23.28
+	Ss
		1259264 DHRS4_PIG (26-276): 1.93e-79: 245: 19.29		DHRS4_PIG (61-326): 3.07e-74: 231: 21.72
+	Ec
		468348 FABG_ECOLI (28-280): 9.82e-83: 252: 20.55		FABG_ECOLI (64-318): 3.16e-71: 222: 25.39
+	At
		1378415 SAG13_ARATH (21-286): 8.42e-79: 243: 21.27		TRNHC_ARATH (60-321): 1.51e-73: 229: 21.97
+	Dm
		1214104 Q8SX57_DROME (29-280): 1.47e-80: 247: 22.48		Q8IPP8_DROME (64-322): 1.29e-71: 224: 22.31
+	At
		1378414 SAG13_ARATH (21-286): 8.42e-79: 243: 21.27		SAG13_ARATH (56-321): 3.71e-73: 228: 20.15
+	Hs
		1162732 DHRS4_HUMAN (11-276): 8.59e-84: 256: 21.19		DR4L2_HUMAN (22-247): 5.2e-67: 211: 23.35
+	Dm
		1362353 Q9VBU5_DROME (8-332): 1.48e-79: 247: 35.78		Q9W3N1_DROME (22-330): 1.18e-68: 219: 38.17
+	Ce
		1341704 Q9N5G3_CAEEL (29-294): 3.33e-79: 244: 23.21		Q9N5G3_CAEEL (62-321): 3.87e-70: 221: 19.03
+	At
		1378411 SAG13_ARATH (21-286): 8.42e-79: 243: 21.27		TRNH8_ARATH (59-321): 1.01e-68: 217: 21.13
+	At
		1378413 SAG13_ARATH (21-286): 8.42e-79: 243: 21.27		TRNH9_ARATH (60-321): 1.43e-68: 217: 22.26
+	Hs
		1240372 DHRS7_HUMAN (18-329): 4.21e-79: 246: 21.73		DHB11_HUMAN (41-307): 1.18e-62: 202: 23.81