HitPredict

Interactor 1: BTK (Q06187)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)
Gene: BTK

Interactor 2: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	9201297, 22745667
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0050852 - T cell receptor signaling pathway
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 659 Hs			1 443
+	Hs
		991737 ITK_HUMAN (4-657): 0: 688: 49.09		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		763394 FYN_MOUSE (155-653): 0: 530: 34.16		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Mm
		980964 YES_MOUSE (133-653): 1.02e-180: 525: 32.46		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		412149 FYN_HUMAN (155-653): 0: 529: 34.35		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		403437 SRC_MOUSE (164-653): 9.58e-178: 517: 35.14		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		433330 YES_HUMAN (133-653): 5.05e-180: 523: 32.77		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		522933 SRC_HUMAN (164-653): 1.04e-178: 520: 35.14		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		442815 HCK_HUMAN (148-653): 6.89e-174: 507: 34.93		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		454827 FGR_HUMAN (152-653): 2.33e-173: 506: 32.56		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		639447 LYN_MOUSE (154-653): 7.83e-170: 496: 35.12		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		411689 LCK_HUMAN (207-653): 1.53e-171: 500: 38.14		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		789110 FRK_HUMAN (182-659): 3.12e-171: 500: 36.92		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		782780 CSK_HUMAN (207-658): 2.35e-170: 495: 36.01		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		433719 LYN_HUMAN (154-653): 1.58e-168: 493: 34.92		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		763412 FYN_MOUSE (155-653): 0: 530: 34.16		KHDR2_MOUSE (100-443): 8.36e-126: 370: 61.65
+	Hs
		433822 LYN_HUMAN (154-653): 1.58e-168: 493: 34.92		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Dm
		337713 SRC64_DROME (169-653): 9.9e-163: 480: 34.62		Q9W255_DROME (59-398): 6.04e-96: 295: 32.35
+	Hs
		337484 ABL1_HUMAN (181-659): 2.77e-165: 505: 38.76		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Hs
		789069 ABL2_HUMAN (169-659): 5.79e-163: 500: 37.70		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33