HitPredict

Interactor 1: EXOS9 (Q06265)
Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)
Gene: EXOSC9

Interactor 2: MPH6 (Q99547)
M-phase phosphoprotein 6
Gene: MPHOSPH6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.689

Property	Details
Experiments	28877463, 24981860, 33961781, 26496610
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000178 - exosome (RNase complex) GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 1 others more... GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 439 Hs			1 160
+	Hs
		110628 EXOS9_HUMAN (1-439): 3.86e-146: 425: 100.00		H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00
+	Hs
		1284955 EXOS8_HUMAN (1-275): 1.68e-86: 267: 26.98		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		1063758 EXOS7_HUMAN (1-284): 9.95e-83: 257: 26.12		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		1304448 EXOS4_HUMAN (14-277): 2.36e-51: 175: 14.76		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		110631 EXOS4_HUMAN (14-277): 2.36e-51: 175: 14.76		H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00