HitPredict

Interactor 1: SUH (Q06330)
Recombining binding protein suppressor of hairless (CBF-1) (J kappa-recombination signal-binding protein) (RBP-J kappa) (RBP-J) (RBP-JK) (Renal carcinoma antigen NY-REN-30)
Gene: RBPJ

Interactor 2: HES1 (Q14469)
Transcription factor HES-1 (Class B basic helix-loop-helix protein 39) (bHLHb39) (Hairy and enhancer of split 1) (Hairy homolog) (Hairy-like protein) (hHL)
Gene: HES1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.633

The method score is based on:

Property Details
Experiments 16682003, 19866488, 19487031
Identification Methods affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003151 - outflow tract morphogenesis
GO:0003677 - DNA binding
and 15 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 500
Hs

1 280
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024