Interactor 1: SUH (Q06330)
Recombining binding protein suppressor of hairless (CBF-1) (J kappa-recombination signal-binding protein) (RBP-J kappa) (RBP-J) (RBP-JK) (Renal carcinoma antigen NY-REN-30)
Gene: RBPJ

Interactor 2: MAML2 (Q8IZL2)
Mastermind-like protein 2 (Mam-2)
Gene: MAML2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 12370315
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LAG1-DNAbind~MamL-1, MamL-1~TIG_SUH
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007219 - Notch signaling pathway
GO:0007221 - positive regulation of transcription of Notch receptor target
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 500
Hs

1 1156
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024