Interactor 1: SUH (Q06330)
Recombining binding protein suppressor of hairless (CBF-1) (J kappa-recombination signal-binding protein) (RBP-J kappa) (RBP-J) (RBP-JK) (Renal carcinoma antigen NY-REN-30)
Gene: RBPJ
Interactor 2: MAML1 (Q92585)
Mastermind-like protein 1 (Mam-1)
Gene: MAML1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.980 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23022380, 26186194, 26496610, 25609649, 28514442, 33961781, 36129980, 11997524, 19907488, 17284587, 12370315, 21475249 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LAG1-DNAbind~MamL-1, MamL-1~TIG_SUH |
| Common GO terms | GO:0002193 - MAML1-RBP-Jkappa- ICN1 complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007219 - Notch signaling pathway GO:0007221 - positive regulation of transcription of Notch receptor target and 1 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
