HitPredict

Interactor 1: TYRO3 (Q06418)
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)
Gene: TYRO3

Interactor 2: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 890 Hs			1 602
+	Hs
		305100 EPHA4_HUMAN (119-820): 7.18e-173: 528: 20.61		RIMB1_HUMAN (21-511): 1.49e-43: 169: 14.76
+	Hs
		665470 EPHA8_HUMAN (116-808): 3.82e-166: 511: 20.03		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		872528 EPHB4_HUMAN (117-823): 1.31e-155: 483: 19.59		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		1189813 EPHA6_HUMAN (129-817): 5.93e-164: 506: 19.46		MYH14_HUMAN (127-597): 5.01e-26: 116: 13.49
+	Hs
		665375 EPHA3_HUMAN (125-821): 0: 552: 19.39		MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78
+	Hs
		972340 TIE2_HUMAN (37-796): 3.68e-160: 499: 23.35		MYH14_HUMAN (127-597): 5.01e-26: 116: 13.49
+	Hs
		990483 EPHAA_HUMAN (203-842): 1.14e-129: 416: 23.35		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		435621 IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		411364 INSR_HUMAN (292-790): 2.17e-60: 226: 31.15		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		981864 RON_HUMAN (500-793): 2.58e-59: 223: 41.95		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		445846 ROS1_HUMAN (279-787): 2.73e-55: 211: 30.76		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		434179 RET_HUMAN (514-790): 1.89e-55: 210: 39.93		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		337444 ABL1_HUMAN (519-878): 6.21e-54: 205: 36.76		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		537734 INSRR_HUMAN (513-780): 3.2e-53: 204: 39.56		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Mm
		554966 MET_MOUSE (495-790): 6.45e-65: 239: 41.67		CTRO_MOUSE (123-595): 8.1e-17: 86.9: 12.24
+	Mm
		555031 MET_MOUSE (495-790): 6.45e-65: 239: 41.67		MYH9_MOUSE (5-481): 5.09e-16: 84.1: 12.68
+	Mm
		555012 MET_MOUSE (495-790): 6.45e-65: 239: 41.67		MYH14_MOUSE (113-600): 1.01e-11: 70.4: 13.23
+	Mm
		554992 MET_MOUSE (495-790): 6.45e-65: 239: 41.67		MRCKA_MOUSE (389-602): 2.28e-09: 62.9: 14.16
+	Hs
		169171 MUSK_HUMAN (42-257): 7.52e-27: 119: 16.59		CKAP4_HUMAN (1-602): 2e-38: 151: 100.00
+	Hs
		983639 FAK1_HUMAN (510-832): 6.04e-53: 202: 35.14		RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47