HitPredict

Interactor 1: TYRO3 (Q06418)
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)
Gene: TYRO3

Interactor 2: DSC3 (Q14574)
Desmocollin-3 (Cadherin family member 3) (Desmocollin-4) (HT-CP)
Gene: DSC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 890 Hs			1 896
+	Hs
		872600 EPHB4_HUMAN (117-823): 1.31e-155: 483: 19.59		PCDG6_HUMAN (1-818): 0: 732: 18.48
+	Hs
		441505 MET_HUMAN (495-790): 3.89e-65: 240: 41.67		DSC3_HUMAN (1-896): 0: 847: 100.00
+	Hs
		580227 TYRO3_HUMAN (1-890): 0: 746: 100.00		CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55
+	Hs
		872602 EPHB4_HUMAN (117-823): 1.31e-155: 483: 19.59		PCDA8_HUMAN (2-470): 1.82e-86: 298: 16.16
+	Hs
		872601 EPHB4_HUMAN (117-823): 1.31e-155: 483: 19.59		PCDG5_HUMAN (2-464): 1.03e-81: 284: 17.86
+	Hs
		872598 EPHB4_HUMAN (117-823): 1.31e-155: 483: 19.59		PCDB3_HUMAN (2-475): 2.75e-78: 272: 15.99
+	Hs
		600717 EPHA1_HUMAN (203-829): 5.58e-141: 445: 26.19		PCDA8_HUMAN (2-470): 1.82e-86: 298: 16.16
+	Hs
		580213 EPHA4_HUMAN (119-820): 7.18e-173: 528: 20.61		CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55
+	Hs
		580236 EPHA7_HUMAN (116-823): 2.21e-172: 528: 20.33		CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55
+	Hs
		521744 EPHA2_HUMAN (116-832): 1.86e-165: 509: 21.01		CADH1_HUMAN (2-464): 1.66e-38: 157: 15.98
+	Hs
		872427 EPHA5_HUMAN (125-818): 6.7e-176: 538: 20.30		DSC2_HUMAN (3-350): 7.18e-27: 120: 13.83
+	Hs
		665396 EPHA3_HUMAN (125-821): 0: 552: 19.39		DSG2_HUMAN (69-391): 3.52e-20: 98.5: 17.85
+	Hs
		872632 EPHA4_HUMAN (119-820): 7.18e-173: 528: 20.61		DSC2_HUMAN (3-350): 7.18e-27: 120: 13.83
+	Hs
		971014 EPHA7_HUMAN (116-823): 2.21e-172: 528: 20.33		DSC2_HUMAN (3-350): 7.18e-27: 120: 13.83
+	Hs
		872440 EPHA5_HUMAN (125-818): 6.7e-176: 538: 20.30		DSG2_HUMAN (69-391): 3.52e-20: 98.5: 17.85
+	Hs
		665215 EPHA2_HUMAN (116-832): 1.86e-165: 509: 21.01		DSC2_HUMAN (3-350): 7.18e-27: 120: 13.83
+	Hs
		1048589 EPHA7_HUMAN (116-823): 2.21e-172: 528: 20.33		DSG2_HUMAN (69-391): 3.52e-20: 98.5: 17.85
+	Hs
		872645 EPHA4_HUMAN (119-820): 7.18e-173: 528: 20.61		DSG2_HUMAN (69-391): 3.52e-20: 98.5: 17.85
+	Hs
		441427 MET_HUMAN (495-790): 3.89e-65: 240: 41.67		CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55
+	Hs
		441414 MET_HUMAN (495-790): 3.89e-65: 240: 41.67		CADH1_HUMAN (2-464): 1.66e-38: 157: 15.98