HitPredict

Interactor 1: PIN3 (Q06449)
[PSI+] inducibility protein 3 (LAS seventeen-binding protein 2) (LAS17-binding protein 2)
Gene: PIN3

Interactor 2: LAS17 (Q12446)
Proline-rich protein LAS17
Gene: LAS17

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.738

Property	Details
Experiments	11743162, 10512884, 23509072, 19841731, 21777813, 23577202
Identification Methods	two hybrid, affinity chromatography technology, unspecified method, protein complementation assay, anti tag coimmunoprecipitation, phage display, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030479 - actin cortical patch
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Sc			1 633
+	Sc
		861166 LSB1_YEAST (1-215): 8.56e-34: 122: 46.28		LAS17_YEAST (1-633): 8.22e-51: 188: 100.00
+	Hs
		126930 GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Hs
		126950 SH3K1_HUMAN (10-117): 3.28e-18: 84.2: 20.35		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Rn
		192354 SH3G2_RAT (10-115): 7.07e-29: 112: 20.76		SYNJ1_RAT (131-630): 3.06e-28: 123: 13.09
+	Rn
		192356 SH3G3_RAT (31-113): 9.2e-28: 109: 27.71		SYNJ1_RAT (131-630): 3.06e-28: 123: 13.09
+	Rn
		193638 SH3G1_RAT (16-113): 2.79e-27: 108: 28.28		SYNJ1_RAT (131-630): 3.06e-28: 123: 13.09
+	Hs
		203249 SH3G2_HUMAN (10-115): 9.95e-29: 111: 20.76		SYNJ1_HUMAN (89-538): 6.62e-22: 103: 12.06
+	Hs
		203248 SH3G1_HUMAN (16-113): 2.65e-27: 108: 28.28		SYNJ1_HUMAN (89-538): 6.62e-22: 103: 12.06
+	Hs
		790657 GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54		WASP_HUMAN (3-448): 2.5e-27: 117: 16.52
+	Hs
		924703 GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54		MINK1_HUMAN (219-528): 2.74e-23: 107: 18.10
+	Hs
		203218 GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54		SYNJ1_HUMAN (89-538): 6.62e-22: 103: 12.06
+	Hs
		554292 GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54		MUC1_HUMAN (148-625): 1.36e-21: 102: 14.37
+	Hs
		203241 SH3K1_HUMAN (10-117): 3.28e-18: 84.2: 20.35		SYNJ1_HUMAN (89-538): 6.62e-22: 103: 12.06
+	Mm
		88459 SH3G2_MOUSE (10-115): 7.36e-29: 112: 20.76		D3Z656_MOUSE (295-625): 3.14e-11: 69: 13.22
+	Mm
		88460 SH3G3_MOUSE (9-116): 2.79e-27: 108: 27.78		D3Z656_MOUSE (295-625): 3.14e-11: 69: 13.22
+	Mm
		101448 SH3G1_MOUSE (33-113): 9.01e-27: 106: 30.49		F8VPR5_MOUSE (175-602): 5.56e-09: 61.7: 12.93
+	Hs
		924669 GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54		TARSH_HUMAN (173-541): 7.04e-12: 70.7: 19.73
+	Hs
		924760 GRB2_HUMAN (59-109): 8.42e-20: 85.3: 36.54		PRG4_HUMAN (100-599): 1.23e-09: 63.7: 10.20
+	Hs
		1056870 STAC2_HUMAN (36-132): 8.53e-19: 85.3: 31.96		MDC1_HUMAN (132-620): 1.5e-09: 63.6: 11.20
+	Hs
		1056926 SH3K1_HUMAN (10-117): 3.28e-18: 84.2: 20.35		MDC1_HUMAN (132-620): 1.5e-09: 63.6: 11.20