HitPredict

Interactor 1: MTG8 (Q06455)
Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2)
Gene: RUNX1T1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11533236
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 488
+	Hs
		987411 MTG8_HUMAN (1-604): 0: 935: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177273 MTG8_HUMAN (1-604): 0: 935: 100.00		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		253997 MTG16_HUMAN (30-604): 0: 772: 69.18		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		253976 MTG16_HUMAN (30-604): 0: 772: 69.18		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177133 MTG8R_HUMAN (32-591): 0: 778: 64.77		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		177150 MTG16_HUMAN (30-604): 0: 772: 69.18		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		987465 MTG8_HUMAN (1-604): 0: 935: 100.00		HDAC8_HUMAN (33-372): 1.01e-137: 403: 43.40
+	Hs
		254003 MTG16_HUMAN (30-604): 0: 772: 69.18		HDAC8_HUMAN (33-372): 1.01e-137: 403: 43.40
+	Hs
		254014 MTG16_HUMAN (30-604): 0: 772: 69.18		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		1270523 ZMYD8_HUMAN (465-591): 3.04e-31: 131: 25.19		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1038402 ZMY11_HUMAN (393-555): 4.69e-54: 195: 19.66		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038817 ZMYD8_HUMAN (465-591): 3.04e-31: 131: 25.19		HDAC1_HUMAN (1-443): 0: 642: 90.07