HitPredict

Interactor 1: MTNA (Q06489)
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)
Gene: MRI1

Interactor 2: MTNA (Q06489)
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)
Gene: MRI1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 15215245, 18719252
Identification Methods x-ray crystallography, two hybrid
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IF-2B~IF-2B
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0019284 - L-methionine salvage from S-adenosylmethionine
GO:0019509 - L-methionine salvage from methylthioadenosine
GO:0046523 - S-methyl-5-thioribose-1-phosphate isomerase activity
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 411
Sc

1 411
+ Hs
+ Sp
+ Hs
+ Hs
+ Hs
+ Dm
+ Sp
+ Sc
+ Sc
+ Hs
+ Hs
+ Sc
+ Hv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024