HitPredict

Interactor 1: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Interactor 2: LG3BP (Q08380)
Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K)
Gene: LGALS3BP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 632 Hs			1 585
+	Hs
		988923 FMR1_HUMAN (1-632): 0: 1106: 100.00		KLH12_HUMAN (127-458): 1e-96: 308: 13.95
+	Hs
		843633 FXR1_HUMAN (1-334): 0: 604: 73.95		LG3BP_HUMAN (1-585): 0: 646: 100.00
+	Hs
		672659 FMR1_HUMAN (1-632): 0: 1106: 100.00		CD6_HUMAN (20-73): 5.91e-09: 60.9: 37.04
+	Mm
		1142923 FXR1_MOUSE (1-334): 0: 596: 73.65		KEAP1_MOUSE (110-507): 4e-81: 268: 14.46
+	Hs
		844027 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		LG3BP_HUMAN (1-585): 0: 646: 100.00
+	Hs
		843979 FXR1_HUMAN (1-334): 0: 604: 73.95		LOXL2_HUMAN (24-125): 1.86e-18: 91.3: 34.82
+	Hs
		672647 FXR1_HUMAN (1-334): 0: 604: 73.95		CD6_HUMAN (20-73): 5.91e-09: 60.9: 37.04
+	Hs
		844302 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		LOXL2_HUMAN (24-125): 1.86e-18: 91.3: 34.82
+	Hs
		672648 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		CD6_HUMAN (20-73): 5.91e-09: 60.9: 37.04