HitPredict

Interactor 1: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 632 Hs			1 1121
+	Mm
		729509 FMR1_MOUSE (1-632): 0: 1063: 93.99		NIPBL_MOUSE (210-1111): 4.04e-61: 232: 12.71
+	Hs
		125399 FMR1_HUMAN (1-632): 0: 1106: 100.00		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		989122 FMR1_HUMAN (1-632): 0: 1106: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Mm
		729554 FMR1_MOUSE (1-632): 0: 1063: 93.99		RHG24_MOUSE (150-802): 1.15e-49: 191: 14.27
+	Hs
		843739 FXR1_HUMAN (1-334): 0: 604: 73.95		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Mm
		729556 FMR1_MOUSE (1-632): 0: 1063: 93.99		ITCH_MOUSE (43-213): 6.22e-16: 85.1: 17.05
+	Mm
		729424 FMR1_MOUSE (1-632): 0: 1063: 93.99		NEDD4_MOUSE (14-322): 7.06e-14: 78.5: 11.64
+	Mm
		1154098 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		NIPBL_MOUSE (210-1111): 4.04e-61: 232: 12.71
+	Mm
		1207055 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		RHG24_MOUSE (150-802): 1.15e-49: 191: 14.27
+	Hs
		843764 FXR1_HUMAN (1-334): 0: 604: 73.95		RHG22_HUMAN (139-801): 2.51e-55: 207: 14.66
+	Hs
		843917 FXR1_HUMAN (1-334): 0: 604: 73.95		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Mm
		1142910 FXR1_MOUSE (1-334): 0: 596: 73.65		AFAD_MOUSE (329-1052): 1.32e-48: 191: 11.79
+	Hs
		125254 FXR1_HUMAN (1-334): 0: 604: 73.95		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Mm
		1207058 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		ITCH_MOUSE (43-213): 6.22e-16: 85.1: 17.05
+	Mm
		808366 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		NEDD4_MOUSE (14-322): 7.06e-14: 78.5: 11.64
+	Hs
		843902 FXR1_HUMAN (1-334): 0: 604: 73.95		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Mm
		808357 FXR1_MOUSE (1-334): 0: 596: 73.65		NEDD4_MOUSE (14-322): 7.06e-14: 78.5: 11.64
+	Hs
		844145 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		125255 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		844241 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84