HitPredict

Interactor 1: PRDX1 (Q06830)
Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1)
Gene: PRDX1

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29929436
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007249 - canonical NF-kappaB signal transduction
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 199 Hs			1 522
+	Hs
		670776 PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		989292 PRDX1_HUMAN (1-199): 2.21e-105: 302: 100.00		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		301779 PRDX1_HUMAN (1-199): 2.21e-105: 302: 100.00		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		685685 PRDX2_HUMAN (1-198): 2.38e-103: 297: 77.78		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		989385 PRDX1_HUMAN (1-199): 2.21e-105: 302: 100.00		TRIM4_HUMAN (61-336): 6.36e-43: 161: 12.90
+	Hs
		989274 PRDX1_HUMAN (1-199): 2.21e-105: 302: 100.00		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59
+	Hs
		989384 PRDX1_HUMAN (1-199): 2.21e-105: 302: 100.00		TRI31_HUMAN (58-334): 3.02e-35: 138: 15.00