HitPredict

Interactor 1: SOX4 (Q06945)
Transcription factor SOX-4
Gene: SOX4

Interactor 2: CTR9 (Q6PD62)
RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1)
Gene: CTR9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25969425
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 1173
+	Hs
		818167 SOX2_HUMAN (21-334): 7.94e-41: 150: 25.48		CTR9_HUMAN (1-1173): 0: 592: 100.00
+	Hs
		297505 TOX4_HUMAN (5-420): 9.74e-34: 136: 10.90		CTR9_HUMAN (1-1173): 0: 592: 100.00
+	Hs
		996719 SSRP1_HUMAN (20-224): 2.93e-30: 126: 18.05		CTR9_HUMAN (1-1173): 0: 592: 100.00
+	Mm
		818742 SOX2_MOUSE (22-334): 9.23e-41: 150: 25.88		OGT1_MOUSE (10-501): 1.06e-43: 175: 13.19
+	Hs
		183080 SOX2_HUMAN (21-334): 7.94e-41: 150: 25.48		KDM6A_HUMAN (4-261): 4.06e-20: 99.1: 11.03
+	Hs
		183153 SOX7_HUMAN (36-291): 1.12e-34: 135: 25.76		KDM6A_HUMAN (4-261): 4.06e-20: 99.1: 11.03
+	Hs
		183046 SOX15_HUMAN (14-239): 6.02e-36: 134: 31.44		KDM6A_HUMAN (4-261): 4.06e-20: 99.1: 11.03
+	Hs
		183091 SOX10_HUMAN (3-380): 3.2e-30: 124: 23.47		KDM6A_HUMAN (4-261): 4.06e-20: 99.1: 11.03
+	Hs
		183081 SOX9_HUMAN (7-388): 1.01e-29: 123: 20.31		KDM6A_HUMAN (4-261): 4.06e-20: 99.1: 11.03
+	Hs
		183160 SOX17_HUMAN (2-281): 6.77e-29: 119: 25.17		KDM6A_HUMAN (4-261): 4.06e-20: 99.1: 11.03
+	Hs
		300239 CIC_HUMAN (38-288): 5.72e-37: 147: 21.91		PRP6_HUMAN (32-285): 7.01e-11: 68.7: 12.02
+	Hs
		300122 SSRP1_HUMAN (20-224): 2.93e-30: 126: 18.05		PRP6_HUMAN (32-285): 7.01e-11: 68.7: 12.02