HitPredict

Interactor 1: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30581152
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 602 Hs			1 440
+	Hs
		1037024 MTCL1_HUMAN (14-552): 1.35e-29: 127: 14.00		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		148772 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036751 RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036697 CNTRL_HUMAN (127-595): 4.34e-09: 61.9: 13.20		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1206000 RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47		MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19
+	Hs
		1192475 CNTRL_HUMAN (127-595): 4.34e-09: 61.9: 13.20		MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19
+	Hs
		990445 CKAP4_HUMAN (1-602): 2e-38: 151: 100.00		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78
+	Dm
		1303397 MYSN_DROME (4-602): 2.13e-21: 101: 10.36		Q9VJ14_DROME (108-231): 3.23e-23: 104: 25.40
+	Mm
		1118137 MYH10_MOUSE (29-602): 1.93e-20: 98.3: 9.45		HERC2_MOUSE (120-197): 2.07e-12: 71.7: 32.50
+	Hs
		319939 RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		1056089 RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78