HitPredict

Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: KIF14 (Q15058)
Kinesin-like protein KIF14
Gene: KIF14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31586073, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008284 - positive regulation of cell population proliferation GO:0043066 - negative regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1748 Hs			1 1648
+	Hs
		1066390 PALS1_HUMAN (272-806): 1.75e-82: 288: 15.67		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		1066234 MPP7_HUMAN (310-807): 3.29e-83: 287: 14.96		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		280044 MPDZ_HUMAN (31-489): 8.85e-18: 92.6: 13.61		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		1021494 DLG1_HUMAN (263-512): 3.61e-17: 90: 16.54		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Ce
		619838 LIN2_CAEEL (104-806): 1.27e-90: 319: 12.90		UN104_CAEEL (357-1160): 1.12e-137: 468: 36.26
+	Hs
		159161 CSKP_HUMAN (217-806): 6.5e-86: 305: 14.66		KINH_HUMAN (356-1198): 1.07e-143: 470: 20.59
+	Hs
		159121 CSKP_HUMAN (217-806): 6.5e-86: 305: 14.66		KIF1B_HUMAN (354-1169): 6.58e-123: 428: 27.52
+	Hs
		231550 MPP7_HUMAN (310-807): 3.29e-83: 287: 14.96		KIF1B_HUMAN (354-1169): 6.58e-123: 428: 27.52
+	Hs
		159288 CSKP_HUMAN (217-806): 6.5e-86: 305: 14.66		KI26A_HUMAN (47-708): 5.21e-109: 387: 17.53
+	Hs
		116734 CSKP_HUMAN (217-806): 6.5e-86: 305: 14.66		KIF2A_HUMAN (163-845): 1.24e-108: 364: 20.90
+	Mm
		702841 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		KIF5A_MOUSE (352-1231): 5.58e-145: 475: 20.80
+	Mm
		660025 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		KIF3A_MOUSE (348-951): 4.89e-143: 459: 26.69
+	Hs
		942384 DLG4_HUMAN (1-112): 2.58e-27: 122: 29.92		KI13B_HUMAN (356-1164): 2.11e-131: 453: 33.45
+	Mm
		93501 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		E9Q4K7_MOUSE (356-1163): 1.47e-127: 442: 33.05
+	Hs
		1020223 PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63		KI13B_HUMAN (356-1164): 2.11e-131: 453: 33.45
+	Hs
		231496 DLG4_HUMAN (1-112): 2.58e-27: 122: 29.92		KIF1B_HUMAN (354-1169): 6.58e-123: 428: 27.52
+	Rn
		292059 DLG4_RAT (1-112): 1.95e-27: 122: 29.92		KIF1B_RAT (354-1156): 5.21e-123: 428: 27.59
+	Dm
		54780 DLG1_DROME (1-118): 1.51e-24: 114: 25.00		A1ZA18_DROME (354-1161): 1.06e-116: 410: 34.22
+	Hs
		231509 DLG1_HUMAN (263-512): 3.61e-17: 90: 16.54		KIF1B_HUMAN (354-1169): 6.58e-123: 428: 27.52
+	Mm
		660012 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		KIF2A_MOUSE (163-845): 1.33e-108: 364: 21.21