HitPredict

Interactor 1: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	16944923
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1748 Hs			1 449
+	Hs
		990875 ZO1_HUMAN (1-1748): 0: 925: 100.00		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		428157 ZO1_HUMAN (1-1748): 0: 925: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Mm
		251095 CSKP_MOUSE (217-806): 7.91e-86: 304: 14.66		TBA1C_MOUSE (1-449): 0: 733: 99.33
+	Hs
		159233 CSKP_HUMAN (217-806): 6.5e-86: 305: 14.66		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Mm
		251099 CSKP_MOUSE (217-806): 7.91e-86: 304: 14.66		TBB5_MOUSE (1-439): 0: 699: 41.00
+	Mm
		934067 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		TBA1C_MOUSE (1-449): 0: 733: 99.33
+	Mm
		933701 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		TBA4A_MOUSE (1-448): 0: 724: 96.21
+	Mm
		399092 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		TBA1B_MOUSE (1-439): 0: 717: 99.09
+	Mm
		934069 INADL_MOUSE (60-508): 1.05e-18: 95.7: 20.29		TBA1C_MOUSE (1-449): 0: 733: 99.33
+	Hs
		1020185 PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Mm
		958391 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		TBB5_MOUSE (1-439): 0: 699: 41.00
+	Mm
		934046 DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92		TBB4B_MOUSE (1-437): 0: 697: 40.73
+	Hs
		942377 DLG4_HUMAN (1-112): 2.58e-27: 122: 29.92		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Mm
		933722 INADL_MOUSE (60-508): 1.05e-18: 95.7: 20.29		TBA1A_MOUSE (1-439): 0: 715: 99.09
+	Hs
		1021520 DLG1_HUMAN (263-512): 3.61e-17: 90: 16.54		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Ce
		105551 DLG1_CAEEL (259-528): 1.27e-15: 85: 15.11		TBA2_CAEEL (1-439): 0: 702: 88.38