HitPredict

Interactor 1: BDF2 (Q07442)
Bromodomain-containing factor 2
Gene: BDF2

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 638 Sc			1 134
+	Sc
		392214 BDF2_YEAST (1-621): 1.67e-129: 397: 100.00		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392584 BDF2_YEAST (1-621): 1.67e-129: 397: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Sp
		391996 YK82_SCHPO (4-626): 1.53e-99: 321: 21.67		H2A1_SCHPO (10-133): 1.77e-51: 161: 56.80
+	Sc
		728789 BDF1_YEAST (60-631): 1.57e-89: 294: 36.20		H2AZ_YEAST (1-134): 2.81e-53: 165: 100.00
+	Sc
		392389 BDF1_YEAST (60-631): 1.57e-89: 294: 36.20		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		1087066 PHIP_HUMAN (85-520): 8.11e-65: 234: 17.05		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Hs
		470106 PHIP_HUMAN (85-520): 8.11e-65: 234: 17.05		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Mm
		101453 F8VPR5_MOUSE (231-431): 3.32e-36: 148: 24.39		H2A3_MOUSE (7-133): 1.38e-51: 161: 57.03
+	Hs
		1066979 BRD3_HUMAN (296-491): 2.95e-27: 119: 20.41		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Hs
		1067038 BRD3_HUMAN (296-491): 2.95e-27: 119: 20.41		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		1067005 BRD3_HUMAN (296-491): 2.95e-27: 119: 20.41		H2A2A_HUMAN (7-133): 1.23e-51: 161: 55.47
+	Hs
		244848 BRD4_HUMAN (278-457): 1.37e-25: 114: 22.22		H2A1J_HUMAN (7-133): 2.47e-52: 163: 55.47
+	Hs
		244634 BRD4_HUMAN (278-457): 1.37e-25: 114: 22.22		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		244795 BRD4_HUMAN (278-457): 1.37e-25: 114: 22.22		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		1067021 BRD3_HUMAN (296-491): 2.95e-27: 119: 20.41		H2AV_HUMAN (10-134): 1.67e-40: 133: 67.72
+	Hs
		243835 BRD4_HUMAN (278-457): 1.37e-25: 114: 22.22		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		244595 BRD4_HUMAN (278-457): 1.37e-25: 114: 22.22		H2AV_HUMAN (10-134): 1.67e-40: 133: 67.72
+	Hs
		469949 BRD2_HUMAN (445-637): 1.38e-24: 111: 14.21		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		243783 BRD4_HUMAN (278-457): 1.37e-25: 114: 22.22		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391554 BRD2_HUMAN (445-637): 1.38e-24: 111: 14.21		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83