HitPredict

Interactor 1: KRA11 (Q07627)
Keratin-associated protein 1-1 (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7)
Gene: KRTAP1-1

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 177 Hs			1 728
+	Hs
		1252431 KR412_HUMAN (2-164): 3.84e-19: 82.1: 32.94		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252456 KRA93_HUMAN (2-144): 5.42e-19: 80.9: 32.90		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		889593 KR108_HUMAN (1-138): 3.84e-17: 78.2: 31.21		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252458 KRA42_HUMAN (16-164): 4.25e-18: 77.8: 30.87		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252455 KRA98_HUMAN (69-173): 4.66e-12: 62.4: 24.76		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252457 KRA92_HUMAN (69-164): 1.22e-10: 59: 29.17		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1252459 KRA24_HUMAN (19-110): 6.46e-11: 59: 28.72		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		473321 KRA23_HUMAN (19-110): 6.46e-11: 59: 28.72		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Mm
		1143407 TENR_MOUSE (20-173): 3.96e-18: 82.8: 19.28		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40
+	Mm
		82714 B9EJ72_MOUSE (63-173): 3.61e-09: 57: 20.29		DLG4_MOUSE (267-582): 4.16e-21: 100: 16.40