HitPredict

Interactor 1: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Interactor 2: PTK6 (Q13882)
Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)
Gene: PTK6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	31980649, 10913193, unassigned2173
Identification Methods	affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 443 Hs			1 451
+	Mm
		763394 KHDR1_MOUSE (1-443): 0: 514: 94.36		FYN_MOUSE (10-450): 0: 521: 42.35
+	Mm
		403437 KHDR1_MOUSE (1-443): 0: 514: 94.36		SRC_MOUSE (3-450): 0: 517: 43.08
+	Hs
		789110 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		FRK_HUMAN (1-447): 0: 526: 41.09
+	Mm
		980964 KHDR1_MOUSE (1-443): 0: 514: 94.36		YES_MOUSE (10-450): 1.7e-179: 514: 42.63
+	Hs
		412149 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		FYN_HUMAN (10-450): 0: 521: 42.35
+	Hs
		522933 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		433330 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		YES_HUMAN (10-450): 0: 519: 42.86
+	Hs
		411689 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		LCK_HUMAN (3-449): 0: 517: 39.07
+	Mm
		639447 KHDR1_MOUSE (1-443): 0: 514: 94.36		LYN_MOUSE (3-449): 3.28e-176: 504: 38.41
+	Hs
		442815 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		HCK_HUMAN (4-449): 8.95e-179: 511: 39.82
+	Hs
		454827 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		FGR_HUMAN (10-450): 3.32e-177: 508: 42.41
+	Hs
		433719 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		LYN_HUMAN (3-449): 5.02e-177: 506: 38.19
+	Hs
		782780 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		CSK_HUMAN (4-448): 3.18e-160: 461: 35.82
+	Hs
		991737 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		ITK_HUMAN (7-447): 1.9e-152: 448: 32.82
+	Mm
		763412 KHDR2_MOUSE (100-443): 8.36e-126: 370: 61.65		FYN_MOUSE (10-450): 0: 521: 42.35
+	Hs
		433822 KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62		LYN_HUMAN (3-449): 5.02e-177: 506: 38.19
+	Hs
		1046410 KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62		PTK6_HUMAN (1-451): 2.09e-175: 500: 100.00
+	Dm
		337713 Q9W255_DROME (59-398): 6.04e-96: 295: 32.35		SRC64_DROME (10-449): 1.52e-164: 476: 42.04
+	Hs
		337484 SF01_HUMAN (82-301): 6.63e-54: 192: 21.33		ABL1_HUMAN (1-449): 2.48e-170: 509: 35.17
+	Hs
		789069 SF01_HUMAN (82-301): 6.63e-54: 192: 21.33		ABL2_HUMAN (2-449): 1.97e-164: 495: 35.02