HitPredict

Interactor 1: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Interactor 2: P55G (Q92569)
Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)
Gene: PIK3R3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21988832
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 443 Hs			1 461
+	Rn
		1144374 KHDR1_RAT (1-443): 0: 515: 94.36		P85A_RAT (60-455): 1.73e-88: 286: 80.05
+	Hs
		655330 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		P85A_HUMAN (48-455): 9.1e-92: 295: 79.17
+	Mm
		763394 KHDR1_MOUSE (1-443): 0: 514: 94.36		FYN_MOUSE (326-459): 6.11e-20: 94.2: 26.06
+	Mm
		403437 KHDR1_MOUSE (1-443): 0: 514: 94.36		SRC_MOUSE (323-459): 7.66e-19: 91.2: 24.14
+	Mm
		980964 KHDR1_MOUSE (1-443): 0: 514: 94.36		YES_MOUSE (317-459): 6.99e-19: 91.2: 23.72
+	Mm
		639447 KHDR1_MOUSE (1-443): 0: 514: 94.36		LYN_MOUSE (298-458): 1.06e-18: 90.4: 24.85
+	Hs
		411689 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		LCK_HUMAN (309-458): 5.54e-21: 97.3: 25.95
+	Hs
		412149 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		FYN_HUMAN (326-459): 6.82e-20: 94.2: 26.06
+	Hs
		442815 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		HCK_HUMAN (310-458): 1.43e-19: 93.1: 26.75
+	Hs
		782780 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		CSK_HUMAN (357-456): 1.18e-19: 93: 34.65
+	Hs
		433330 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		YES_HUMAN (317-459): 6.84e-19: 91.2: 23.72
+	Hs
		522933 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		SRC_HUMAN (323-459): 8.26e-19: 90.8: 24.14
+	Hs
		789110 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		FRK_HUMAN (256-459): 1.27e-18: 90: 24.04
+	Hs
		454827 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		FGR_HUMAN (323-459): 2.54e-18: 89.2: 26.21
+	Hs
		433719 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		LYN_HUMAN (298-458): 6.17e-18: 88.1: 24.85
+	Hs
		548692 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		VAV_HUMAN (65-170): 4e-12: 70.6: 27.36
+	Hs
		433822 KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62		LYN_HUMAN (298-458): 6.17e-18: 88.1: 24.85
+	Mm
		763412 KHDR2_MOUSE (100-443): 8.36e-126: 370: 61.65		FYN_MOUSE (326-459): 6.11e-20: 94.2: 26.06
+	Dm
		113951 Q9W255_DROME (59-398): 6.04e-96: 295: 32.35		M9PAY7_DROME (56-160): 1.96e-11: 64.8: 27.36
+	Dm
		113950 Q9W254_DROME (68-273): 1.11e-66: 220: 39.32		M9PAY7_DROME (56-160): 1.96e-11: 64.8: 27.36