HitPredict

Interactor 1: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.623

Property	Details
Experiments	22745667, 19531213, unassigned1973
Identification Methods	unspecified method, affinity chromatography technology, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0017124 - SH3 domain binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 665
+	Hs
		991928 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		CD2AP_HUMAN (1-664): 1.16e-98: 317: 32.22
+	Hs
		991791 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		SPD2A_HUMAN (1-631): 1.05e-46: 180: 14.72
+	Mm
		1141333 KHDR1_MOUSE (1-443): 0: 514: 94.36		NCK1_MOUSE (104-421): 1.23e-32: 131: 15.93
+	Mm
		1141126 KHDR1_MOUSE (1-443): 0: 514: 94.36		GRB2_MOUSE (2-158): 6.83e-33: 128: 19.91
+	Hs
		557667 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		924509 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		991902 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30
+	Hs
		991778 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		ITSN1_HUMAN (68-454): 2.48e-21: 101: 14.01
+	Hs
		275187 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		GRAP2_HUMAN (1-56): 2.18e-17: 85.8: 32.14
+	Hs
		991805 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		DNMBP_HUMAN (104-607): 3.03e-16: 85.1: 15.82
+	Hs
		209037 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Hs
		548692 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		VAV_HUMAN (84-158): 4.66e-13: 74.7: 28.95
+	Mm
		1141173 KHDR2_MOUSE (100-443): 8.36e-126: 370: 61.65		GRB2_MOUSE (2-158): 6.83e-33: 128: 19.91
+	Dm
		1360803 Q9W255_DROME (59-398): 6.04e-96: 295: 32.35		Q9VA36_DROME (2-576): 1.83e-50: 190: 22.53
+	Hs
		275201 KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62		GRAP2_HUMAN (1-56): 2.18e-17: 85.8: 32.14
+	Hs
		209060 SF01_HUMAN (82-301): 6.63e-54: 192: 21.33		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77