Interactor 1: BAX (Q07812)
Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)
Gene: BAX

Interactor 2: B2LA1 (Q16548)
Bcl-2-related protein A1 (Bcl-2-like protein 5) (Bcl2-L-5) (Hemopoietic-specific early response protein) (Protein BFL-1) (Protein GRS)
Gene: BCL2A1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 10753914, 14766748
Identification Methods two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bcl-2
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005737 - cytoplasm
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0008053 - mitochondrial fusion
and 6 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 192
Hs

1 175
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Last updated: 15 Jul 2024