Interactor 1: BAX (Q07812)
Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)
Gene: BAX

Interactor 2: BAK (Q16611)
Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7)
Gene: BAK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.935

The method score is based on:

Property Details
Experiments 11571294, 33961781, 21712378, 15901672, 16439990, 17289999
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bcl-2
Common GO terms GO:0001782 - B cell homeostasis
GO:0001783 - B cell apoptotic process
GO:0001836 - release of cytochrome c from mitochondria
GO:0001974 - blood vessel remodeling
GO:0002262 - myeloid cell homeostasis
and 37 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 192
Hs

1 211
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024