Interactor 1: BAX (Q07812)
Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)
Gene: BAX

Interactor 2: BBC3B (Q96PG8)
Bcl-2-binding component 3, isoforms 3/4 (JFY-1) (p53 up-regulated modulator of apoptosis)
Gene: BBC3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 34587475
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005739 - mitochondrion
GO:0006915 - apoptotic process
GO:0070059 - intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0090200 - positive regulation of release of cytochrome c from mitochondria
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 192
Hs

1 261
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024