Interactor 1: BAX (Q07812)
Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)
Gene: BAX

Interactor 2: ASC (Q9ULZ3)
Apoptosis-associated speck-like protein containing a CARD (hASC) (Caspase recruitment domain-containing protein 5) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1)
Gene: PYCARD

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.696

The method score is based on:

Property Details
Experiments 14730312
Identification Methods anti tag coimmunoprecipitation, pull down, confocal microscopy, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~CARD
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
and 6 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 192
Hs

1 195
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024