HitPredict

Interactor 1: BAX (Q07812)
Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)
Gene: BAX

Interactor 2: SHLB1 (Q9Y371)
Endophilin-B1 (Bax-interacting factor 1) (Bif-1) (SH3 domain-containing GRB2-like protein B1)
Gene: SH3GLB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.664

The method score is based on:

Property Details
Experiments 11161816, 11259440, 19074440
Identification Methods two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0008289 - lipid binding
and 3 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 192
Hs

1 365
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024