HitPredict

Interactor 1: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.826

Property	Details
Experiments	18719108, 21900206
Identification Methods	unspecified method, x-ray crystallography, two hybrid, surface plasmon resonance, peptide array
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	Ank_2~Bcl-2
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042803 - protein homodimerization activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 1128
+	Hs
		489414 BCL2_HUMAN (5-231): 3.01e-71: 219: 44.16		ASPP2_HUMAN (1-1128): 0: 599: 100.00
+	Hs
		1043718 B2CL2_HUMAN (6-231): 3.69e-51: 166: 39.38		ASPP2_HUMAN (1-1128): 0: 599: 100.00
+	Hs
		310048 MCL1_HUMAN (36-195): 4.35e-36: 131: 25.00		TNKS1_HUMAN (808-1080): 1.68e-44: 178: 12.84
+	Hs
		992198 MCL1_HUMAN (36-195): 4.35e-36: 131: 25.00		TNKS2_HUMAN (893-1127): 6.78e-43: 172: 14.54