Interactor 1: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Interactor 2: BAD (Q92934)
Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)
Gene: BAD

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 1.00 0.995

The method score is based on:

Property Details
Experiments 15721256, 9305851, 16697956, 20603619, 26186194, 20837658, 28514442, 15705582, 12137781, 27684187, 26871637, 29997244, 12115603, 33961781, 9389483, 18628207, 25416956, 19427857, 10611223, 15694340 and 19 others

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Identification Methods unspecified method, pull down, affinity chromatography technology, two hybrid, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti bait coimmunoprecipitation and 7 others

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Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bcl-2_BAD
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage
and 3 others

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Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 233
Hs

1 168
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024