Interactor 1: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1
Interactor 2: BAD (Q92934)
Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)
Gene: BAD
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.99 | 1.00 | 0.995 |
The method score is based on:
Property | Details |
---|---|
Experiments | 15721256, 9305851, 16697956, 20603619, 26186194, 20837658, 28514442, 15705582, 12137781, 27684187, 26871637, 29997244, 12115603, 33961781, 9389483, 18628207, 25416956, 19427857, 10611223, 15694340 and 19 others
more... |
Identification Methods | unspecified method, pull down, affinity chromatography technology, two hybrid, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti bait coimmunoprecipitation and 7 others
more... |
Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Bcl-2~Bcl-2_BAD |
Common GO terms | GO:0001836 - release of cytochrome c from mitochondria GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage and 3 others more... |
Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024