Interactor 1: MCL1 (Q07820)
Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)
Gene: MCL1

Interactor 2: BBC3B (Q96PG8)
Bcl-2-binding component 3, isoforms 3/4 (JFY-1) (p53 up-regulated modulator of apoptosis)
Gene: BBC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.752

The method score is based on:

Property Details
Experiments 15721256, 16697956, 26186194, 28202514, 28514442, 16007132, 33961781, 21613222, 15694340, 21730980
Identification Methods unspecified method, affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005739 - mitochondrion
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 350
Hs

1 261
+ Hs
+ Hs
+ Hs
+ Hs
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Last updated: 15 Jul 2024