Interactor 1: DPOE1 (Q07864)
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A)
Gene: POLE

Interactor 2: DPOE4 (Q9NR33)
DNA polymerase epsilon subunit 4 (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12)
Gene: POLE4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 27235625, 33961781, 10801849
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006261 - DNA-templated DNA replication
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 2286
Hs

1 117
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024