HitPredict

Interactor 1: KLC1 (Q07866)
Kinesin light chain 1 (KLC 1)
Gene: KLC1

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	24457600, 36517590
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 573 Hs			1 746
+	Hs
		1080390 KLC4_HUMAN (5-571): 4.27e-99: 315: 68.53		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		1080318 KLC2_HUMAN (5-571): 7.66e-95: 304: 68.43		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		1080213 TTC28_HUMAN (62-572): 4.35e-36: 146: 12.60		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		174922 OGT1_HUMAN (382-531): 4.66e-12: 71.2: 13.33		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		1207351 OGT1_MOUSE (382-531): 4.42e-12: 71.2: 13.33		NSD2_MOUSE (275-729): 1.45e-92: 317: 16.03
+	Zm
		25454 A0A1D6JFQ5_MAIZE (1-569): 1.41e-48: 184: 14.19		A0A1D6ISR3_MAIZE (608-732): 3.77e-52: 198: 39.37
+	Hs
		174816 OGT1_HUMAN (382-531): 4.66e-12: 71.2: 13.33		KMT2A_HUMAN (606-733): 6.89e-19: 94.4: 39.54
+	Hs
		165599 OGT1_HUMAN (382-531): 4.66e-12: 71.2: 13.33		SET1A_HUMAN (611-732): 3.19e-18: 92: 38.71