Interactor 1: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1

Interactor 2: FBX28 (Q9NVF7)
F-box only protein 28
Gene: FBXO28

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 27754753, 35813202, 36115843, 36114006, 37596321, 25416956, 27705803, 32296183, 33961781, 37831778, 20596027, 22632967, unassigned1304, 32814053, unassigned3799
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, validated two hybrid, two hybrid prey pooling approach, two hybrid array, luminescence based mammalian interactome mapping, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box~Skp1
Common GO terms GO:0000209 - protein polyubiquitination
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 163
Hs

1 368
+ Dm

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Last updated: 11Aug2025