Interactor 1: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1
Interactor 2: FBXL5 (Q9UKA1)
F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein)
Gene: FBXL5
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.90 | 0.934 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 31167929, 32296183, 10531037, 19762596, 21516116, 27383304, 28514442, 32126207, 33961781, 19762597, 24157836, 24778179, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, biochemical, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | F-box-like~Skp1 |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
