HitPredict

Interactor 1: PPARA (Q07869)
Peroxisome proliferator-activated receptor alpha (PPAR-alpha) (Nuclear receptor subfamily 1 group C member 1)
Gene: PPARA

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	31391242
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 468 Hs			1 548
+	Hs
		740594 PPARG_HUMAN (1-468): 2.71e-112: 342: 54.36		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		992438 PPARA_HUMAN (1-468): 1.4e-141: 415: 100.00		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		262145 ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30		TRIM3_HUMAN (7-525): 5.4e-80: 267: 16.64
+	Hs
		740576 PPARG_HUMAN (1-468): 2.71e-112: 342: 54.36		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		740518 PPARG_HUMAN (1-468): 2.71e-112: 342: 54.36		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		369530 ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		370719 ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Hs
		536747 PPARG_HUMAN (1-468): 2.71e-112: 342: 54.36		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		265849 NR1I2_HUMAN (79-464): 2.55e-103: 316: 24.46		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		369497 ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30		TRI26_HUMAN (12-339): 5.62e-65: 222: 16.23
+	Hs
		370380 ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30		TRIM8_HUMAN (18-465): 8.09e-65: 222: 18.25
+	Hs
		242818 PPARG_HUMAN (1-468): 2.71e-112: 342: 54.36		TRI13_HUMAN (17-333): 3.8e-62: 211: 22.64
+	Hs
		368914 ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		782695 HNF4A_HUMAN (77-464): 1.45e-103: 318: 22.11		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Hs
		659746 RXRB_HUMAN (39-465): 1.39e-104: 323: 21.71		TRIM1_HUMAN (17-367): 3.2e-63: 222: 21.28
+	Hs
		370187 ESR1_HUMAN (11-464): 2.21e-107: 332: 18.30		TRI11_HUMAN (12-402): 5.69e-62: 212: 16.88
+	Hs
		536736 RXRB_HUMAN (39-465): 1.39e-104: 323: 21.71		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		175702 ESR2_HUMAN (2-465): 7.16e-99: 308: 17.18		TRI18_HUMAN (46-330): 5.85e-60: 211: 23.43
+	Hs
		818879 RXRG_HUMAN (2-465): 8.06e-118: 354: 22.72		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		659723 RXRB_HUMAN (39-465): 1.39e-104: 323: 21.71		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39