Interactor 1: SOS1 (Q07889)
Son of sevenless homolog 1 (SOS-1)
Gene: SOS1

Interactor 2: FRS2 (Q8WU20)
Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (Suc1-associated neurotrophic factor target 1) (SNT-1)
Gene: FRS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.906

The method score is based on:

Property Details
Experiments 9797459, 10783152, 9182757, 11997436, 16893902
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRS~PH
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008543 - fibroblast growth factor receptor signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1333
Hs

1 508
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024