HitPredict

Interactor 1: ACK1 (Q07912)
Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)
Gene: TNK2

Interactor 2: SNX9 (Q9Y5X1)
Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A)
Gene: SNX9

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.866

The method score is based on:

Property Details
Experiments 11799118, 16137687, 16316319
Identification Methods affinity chromatography technology, peptide array, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_2~SH3_9
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005905 - clathrin-coated pit
GO:0006897 - endocytosis
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1038
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024