HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: ELAV2 (Q12926)
ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Hel-N1)
Gene: ELAVL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 359
+	Hs
		1020247 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00
+	Hs
		516484 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00
+	Hs
		951937 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00
+	Hs
		474019 PAB4L_HUMAN (17-92): 5.07e-19: 86.6: 19.48		ELAV2_HUMAN (1-359): 5.95e-103: 309: 100.00
+	Hs
		516493 SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		516478 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		516495 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87
+	Hs
		516339 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Hs
		516689 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		PABP3_HUMAN (115-358): 2.14e-42: 157: 20.51
+	Hs
		1028557 SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25		ELAV1_HUMAN (24-120): 1.32e-17: 84.3: 29.90
+	Hs
		516466 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		PABP1_HUMAN (115-358): 1.39e-44: 164: 20.88
+	Zm
		8143 A0A1D6ELH4_MAIZE (5-246): 1.03e-23: 101: 14.58		A0A1D6ELH4_MAIZE (40-277): 9.02e-42: 156: 20.83
+	Hs
		474021 PAB4L_HUMAN (17-92): 5.07e-19: 86.6: 19.48		PABP4_HUMAN (4-282): 1.19e-46: 169: 19.87
+	Hs
		516371 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		RBMS1_HUMAN (37-227): 8.76e-27: 111: 36.55
+	Hs
		516532 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		RBMS2_HUMAN (32-217): 2.99e-25: 107: 36.27
+	Hs
		668339 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		RBMS1_HUMAN (37-227): 8.76e-27: 111: 36.55
+	Hs
		474026 PAB4L_HUMAN (17-92): 5.07e-19: 86.6: 19.48		RBMS2_HUMAN (32-217): 2.99e-25: 107: 36.27
+	Mm
		936671 SRSF3_MOUSE (15-99): 9.33e-28: 105: 43.53		ELAV1_MOUSE (24-120): 1.54e-17: 84.3: 29.90
+	Mm
		936689 SRSF7_MOUSE (11-105): 2e-26: 105: 40.00		ELAV1_MOUSE (24-120): 1.54e-17: 84.3: 29.90