HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 282
+	Hs
		1028541 SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		1028644 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		1028895 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		516493 SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Dm
		580166 Q9V3W7_DROME (11-243): 1.55e-56: 182: 55.65		TRA2_DROME (97-281): 1.36e-44: 153: 43.78
+	Hs
		925020 SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		993707 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Mm
		925167 SRSF9_MOUSE (2-239): 1.21e-65: 204: 58.82		TRA2B_MOUSE (1-279): 2.66e-34: 127: 52.30
+	Dm
		580160 SRR55_DROME (17-183): 2.57e-52: 175: 39.79		TRA2_DROME (97-281): 1.36e-44: 153: 43.78
+	Mm
		192621 SRSF5_MOUSE (14-183): 7.35e-61: 194: 41.48		TRA2B_MOUSE (1-279): 2.66e-34: 127: 52.30
+	Hs
		925021 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		516478 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		925012 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		925011 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		516339 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		516451 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Mm
		857340 SRSF1_MOUSE (1-235): 1.04e-49: 165: 100.00		TIA1_MOUSE (114-207): 2.24e-18: 86: 21.28
+	Mm
		857324 Q542V3_MOUSE (17-198): 2.22e-46: 162: 42.47		TIA1_MOUSE (114-207): 2.24e-18: 86: 21.28
+	Mm
		936481 SRSF1_MOUSE (1-235): 1.04e-49: 165: 100.00		TIAR_MOUSE (113-253): 1.32e-16: 81: 18.52
+	Mm
		665745 PABP1_MOUSE (8-203): 8.27e-38: 141: 16.67		TIA1_MOUSE (114-207): 2.24e-18: 86: 21.28