HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33658012
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 707
+	Hs
		1028587 SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		1028761 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		993788 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		1084357 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		903165 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		516438 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		1028844 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		NLE1_HUMAN (269-366): 5.18e-09: 61.2: 13.86
+	Hs
		992997 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		516754 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		516733 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		FBW1B_HUMAN (614-705): 7.05e-12: 70.5: 25.00
+	Hs
		903258 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		903196 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		952182 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		1084454 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		952150 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		NLE1_HUMAN (269-366): 5.18e-09: 61.2: 13.86
+	Hs
		1031501 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		FBW1A_HUMAN (614-705): 2.9e-12: 72: 26.09
+	Hs
		1031492 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		FBW1B_HUMAN (614-705): 7.05e-12: 70.5: 25.00