HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: WWP1 (Q9H0M0)
NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
Gene: WWP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35264565
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 922
+	Hs
		1028813 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		WWP1_HUMAN (1-922): 0: 953: 100.00
+	Hs
		952117 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		WWP1_HUMAN (1-922): 0: 953: 100.00
+	Hs
		125425 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125426 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		516643 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		ITCH_HUMAN (1-922): 0: 884: 57.14
+	Hs
		125406 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125122 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125374 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125491 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125430 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		808143 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Hs
		1028715 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		HUWE1_HUMAN (130-921): 1.4e-172: 559: 24.48
+	Hs
		992830 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		HUWE1_HUMAN (130-921): 1.4e-172: 559: 24.48
+	Hs
		952015 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		HUWE1_HUMAN (130-921): 1.4e-172: 559: 24.48
+	Sc
		376913 PABP_YEAST (123-203): 2.42e-12: 68.1: 22.73		TOM1_YEAST (439-921): 2.08e-156: 512: 31.81
+	Hs
		992947 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		SMUF1_HUMAN (6-451): 5.28e-38: 154: 15.82