HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: LC7L2 (Q9Y383)
Putative RNA-binding protein Luc7-like 2
Gene: LUC7L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0006376 - mRNA splice site recognition GO:0016607 - nuclear speck
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 392
+	Hs
		1029169 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		1029116 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		LUC7L_HUMAN (1-367): 3.39e-77: 244: 66.49
+	Hs
		992951 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		LUC7L_HUMAN (1-367): 3.39e-77: 244: 66.49
+	Hs
		1329991 PABP3_HUMAN (8-203): 1.09e-33: 129: 16.18		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		308193 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		LC7L3_HUMAN (8-389): 5.72e-58: 196: 28.51
+	Hs
		1084460 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		1084423 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		LUC7L_HUMAN (1-367): 3.39e-77: 244: 66.49
+	Hs
		1031502 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Sc
		376945 PABP_YEAST (123-203): 2.42e-12: 68.1: 22.73		LUC7_YEAST (5-248): 2.16e-65: 210: 30.95
+	Dm
		970879 RBP1_DROME (16-88): 9.45e-29: 107: 49.32		Q9W3X8_DROME (165-279): 2.1e-18: 88.4: 20.00