HitPredict

Interactor 1: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 25416956, 27107012, 32296183, 11266540, unassigned1304
Identification Methods two hybrid, two hybrid array, barcode fusion genetics two hybrid, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TLE_N~TLE_N
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001501 - skeletal system development
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005667 - transcription regulator complex
and 9 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 197
Hs

1 197
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Last updated: 15 Jul 2024