HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26777405
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 466
+	Hs
		1028539 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		516494 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		1030211 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		963512 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		680445 TIA1_HUMAN (98-188): 6.06e-10: 63.1: 17.02		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		516742 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68
+	Sc
		742039 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		BRE5_YEAST (9-441): 5.6e-45: 166: 15.31
+	Hs
		1031497 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68
+	Zm
		22429 A0A1D6I0G1_MAIZE (71-185): 4.45e-09: 60.8: 20.83		A0A1D6Q2L8_MAIZE (6-437): 3.94e-61: 208: 23.45
+	Sc
		376881 PABP_YEAST (72-188): 2.61e-10: 64.6: 14.75		BRE5_YEAST (9-441): 5.6e-45: 166: 15.31
+	Hs
		1073552 RBM4B_HUMAN (3-104): 4.68e-11: 66.1: 23.08		SAFB1_HUMAN (93-439): 7.61e-35: 140: 12.39
+	Hs
		516621 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Mm
		1208011 RBM4_MOUSE (1-218): 3.79e-19: 90.8: 23.85		SRSF9_MOUSE (342-454): 5.28e-14: 73.1: 30.97
+	Hs
		963566 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		CELF4_HUMAN (297-422): 1.94e-13: 74.3: 15.91
+	Hs
		1031413 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29
+	Hs
		963554 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		CELF1_HUMAN (330-419): 3.54e-12: 70: 14.29