HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: PPIG (Q13427)
Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (CASP10) (Clk-associating RS-cyclophilin) (CARS-Cyp) (CARS-cyclophilin) (SR-cyclophilin) (SR-cyp) (SRcyp) (Cyclophilin G) (Rotamase G)
Gene: PPIG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pro_isomerase~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008380 - RNA splicing and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 754
+	Hs
		992754 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		PPIG_HUMAN (1-754): 1.33e-95: 315: 100.00
+	Hs
		1028891 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		PPIG_HUMAN (1-754): 1.33e-95: 315: 100.00
+	Hs
		1028639 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		PPIG_HUMAN (1-754): 1.33e-95: 315: 100.00
+	Hs
		673794 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		NKTR_HUMAN (7-385): 7.16e-67: 243: 52.67
+	Hs
		673791 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		NKTR_HUMAN (7-385): 7.16e-67: 243: 52.67